Amongst a novena of virtual life savers on computers (under Windows XP or seven of course, everything is great with MacOS or Linux), we have the following. If you just want to pick one, pick Everything! Friends keep on thanking me for that.
- file finding via Everything, a ligth-weight freeware to find files and directories with wildcards or regular expressions (then you can easily disable Windows *.* indexing and save hassle, space and time). It revolutionized my way of naming AND storing files (project management, bibliographic references files, mainly)
- USB port cleaning with DriveCleanup when after some use, your usb keys and drives do not mount nicely
- stuff and idea organizing via mindmapping software, for instance FreeMind or FreePlane
- task organizing and GTD (getting things done) via ToDO list
- note taking (simple and yet, simple) via The Guide, or maybe TreeSheet
- word synonyming via Wordnet
- communicating via Skype on usb key (its install is forbidden on my work laptop): copy some new Skype.exe file (from any local installation) to any directory (SkypePortable) on your USB Drive; in that directory create a directory named "Data", above create a file (with a text pad like context or notepad++) called "skype.bat" with command line "skype.exe /datapath:"Data" /removable", that you can launch instead of skype.exe (7zip archive here for Skype version 5.9.0.114). For DIY versions: http://www.gruups.com/usbskype/ or Skype Portable or TheUberOverLord Formally Install Skype to USB Drive Only
- security via Keypass, (open source version), to keep and propose password for management,
- podcasting via Ziepod (or Juice).